The Department of Political Science, Sociology and Anthropology (P.S.A.) was established by the Board of Governors in 1965 as one of the original Departments in the Faculty of Arts. It was dissolved on 19 February 1974. The Department was originally conceived as an experiment in interdisciplinary, and it was responsible, through its Chair, for the promotion of research and the development and delivery of programs which combined the fields of Political Science, Sociology and Anthropology. In 1965, P.S.A. consisted of seven faculty members and offered courses leading to a B.A. degree. In 1966, the number of courses and programs greatly expanded, to include both M.A. and Ph.D. programs. In 1969, the Archaeology program was removed and placed as a distinct unit under the administration of the Faculty of Arts. It later became a full department. The history of P.S.A. was marked by a prolonged period of dissension between faculty members, the Department, and the University which included a period of trusteeship and a strike by students and faculty in 1969, the suspension of faculty, and the subsequent censure of the University by the Canadian Association of University Teachers in May 1971. In 1974, P.S.A. was split into two successor departments: Political Science, and Sociology and Anthropology.

The Department was administered by a Chair and a number of standing committees. The Chair was the chief administrative officer, whose responsibilities included the management of the operational budget; faculty tenure, promotion and salary recommendations; teaching assignments; and representation of the Department to external bodies. The Departmental Assistant was responsible for much of the day-to-day administration and the management of the departmental budget, the scheduling of courses, the provision of liaison with administrative offices, and advising students.

The number and composition of departmental committees varied greatly over time. In 1969, there were eleven committees, including Budget; Curriculum; Executive; Faculty/Staff Relations; Graduate Admissions; Graduate Programme; Grievance; Library; Salary; Tenure and Promotions; Teaching Methods and Grades; and Visiting Lecturers. By the next year, there remained only the Executive, Budget, Curriculum, Graduate Studies, and Appointments committees. This structure remained until the dissolution of the Department. Other short-lived committees, such as Majors and Honours, were also formed. P.S.A. also struck ad hoc committees, such as the Chairman's Search Committee, when required.